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Dr. Matthew Block

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Rochester, MN

MEDICAL Specialty:

Melanoma, Ovarian Cancer, Thyroid Cancer



200 1ST ST SW, ROCHESTER, MN, 559050001
200 1ST ST SW, ROCHESTER, MN, 559050001
507-284-2511
Years of Experience
21 years of experience
NPI Number
1356359111
ABOUT

Dr. Matthew Block, MD, is a distinguished Oncology Specialist based in Rochester, MN, where he practices at the renowned Mayo Clinic. With two decades of experience in the field, Dr. Block has established himself as a trusted expert in oncology, holding board certification in Internal Medicine. His medical journey began at the esteemed Mayo Clinic Alix School of Medicine, where he completed both his medical degree and residency, solidifying his foundation in patient-centered care.

Dr. Block is known for his compassionate and meticulous approach to patient care, frequently treating conditions such as Melanoma, Ovarian Cancer, and Thyroid Cancer. His dedication to understanding each patient’s unique circumstances enables him to provide personalized treatment plans that address both the physical and emotional aspects of cancer care. The consistently high ratings from his patients are a testament to his effectiveness and commitment to exceptional healthcare delivery.

Beyond his clinical expertise, Dr. Block is deeply committed to the well-being of the Rochester community. He is currently accepting new patients and works closely with a variety of insurance providers, including UnitedHealthCare and Blue Cross Blue Shield, to ensure accessibility for those in need. Dr. Block’s unwavering dedication to improving patient outcomes and his genuine care for his patients make him a valued member of the Mayo Clinic team and a beacon of hope for many facing cancer diagnoses.

Education & Certifications
Fellowship

Mayo Clinic Alix School of Medicine

Residency

Mayo Clinic Alix School of Medicine

Medical Education

Mayo Clinic Alix School of Medicine

Board Certifications

Internal Medicine and Medical Oncology

Dr. Matthew Block’s Office Locations
1

MN - Cancer

MN - Cancer, 200 1st St SW, Rochester, MN55905

Directions
Dr. Matthew Block profile image

Published Articles

Long-Term Survival in High-Grade Serous Ovarian Cancer Compared With the General US Population: A 30-Year Landmark Analysis.- 2026 Mar
The Association Between Multiple Myeloma and Neuropsychiatric Manifestations: A Narrative Review.- 2026 Apr
Foundations for Long-Term Implant Success.- 2026 Feb 14
Diagnosis-Specific Links Between Physical Activity and Sleep Duration in Youth with Disabilities: A Systematic Review with Quantitative Synthesis.- 2026 Jan 19
Predicting substance use behaviors with machine learning using small sets of judgment and contextual variables.- 2026 Jan 27
Biomarker analysis of circulating tumor DNA in clinical stage III melanoma patients treated with neoadjuvant immunotherapy combined with targeted therapy.- 2026
Dyslipidemia-associated natural IgM improves oncolytic virus TILT-123 efficacy through antibody-dependent enhancement in solid tumors.- 2026 Jan 20
Beyond the surface: soluble SIGLEC-1 as a clinically applicable type I IFN biomarker.- 2026 Feb 4
An Integrated Analysis of Four Targeted Thorium Conjugates to Assess the (227)Th and (223)Ra Distribution and Tissue-Related Radiation.- 2025 Dec 24
Tucatinib and trastuzumab emtansine for patients with previously treated HER2-positive locally advanced and metastatic breast cancer: primary analysis of the randomized phase III trial HER2CLIMB-02.- 2026 Mar

Clinical Trials

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer
Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary
MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma
CM-101 in NASH Patients - The SPLASH Study
VALOR: The Talent Thoracic Stent Graft System Clinical Study
Diagnostic Yield of an Ambulatory Patch Monitor in Unexplained Emergency Department Syncope: A Pilot Study (PATCH-ED)
Neoadjuvant Pembrolizumab and Axitinib in Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus
Tafasitamab and Zanubrutinib for the Treatment of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, TaZA CLL Study
A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

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